yes it can but there needs to be mythic loot that drops from enemy.
i only have 1 screenshot for evidence - this was during labyrinth event.
im sure it works elsewhere though, as long as theres a mythic item and arcane item in the same loot table.
for super rare items such as immortal shackle - idk, perhaps its alone in its own loot table.
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also have some other crap attached
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