So I got Weakness last night, dropped Blessing of Vitality for it, with the rationale that if I debuff my opponent's damage, it will offset the armor I'm giving up from my buff, while also debuffing my opponent's dodge rate. There seems to be one major problem, and I still have to test this: when I'm trying to debuff someone who has 75% Dodge, my debuff is going to get dodged a lot! It might be better to have self buffs that you're sure are going to be there rather than worrying about your spells missing someone over and over and over.

Again, I still have to verify that debuffs can be dodged, but if this is the case then I might go back to Blessing of Vitality and wait for an expansion to add points to the new debuffs. I'll post my findings after I have more chance to test.