Depends ..

If you wanna steal kills, go 150str, rest dex, with bow;
If u wanna solo boss using 1000 pots, go dagger set 150str, rest dex;
If you wanna tank and kill less, but having high survivability, go 150 str, rest dex, using sword crafted orlok shield/sword set;
If you wanna tank and kill rarely, but surviving without using many pots, go full str (avoid doing so cuz ur hit% is 66.. In a word u miss all

I hope it helped cya