I remember going through the same questions you are when I hit 50, lol. I ended up going int/str. I regret that deeply.
Here's what I would do for..
Items
Do what Walkhardd suggested, use all sewers items. Wand sets are going to be your best friend for a while.
And always use gemstone wands over the others, they give the most damage, if I remember correctly.
Stats
Keep lowest dex for your level items, and rest onto Int. The reasons I do this is 1: for extra hit %, and 2: the extra weapon damage.
Spell Build
While I see why you want the debuffs, you really should reconsider weakness. Believe me: drain, frostbite and icestorm are better than weakness. Nightmare is alright, but I would've waited on that one too. ;p You want to maximize your skill damage, and after AO, the debuffs stop being very useful lol.
This is all my preference, feel free to ignore me completely. ;o
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