I don't think you can set hotkeys besides skills (1-9 or something) but heres a list of pre-set hotkeys

Quote Originally Posted by Samhayne View Post
WASD to move
Q and E turn you
Spacebar to auto attack
Number keys to fire off your different attacks.
r = switch bank of abilities
i = inventory
c = avatar
[ = health potion
] = mana potion
m = minimap.